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Potential concerns include: Unknown product quality Contamination or sterility issues Incorrect dosing Injection site reactions Allergic or immune reactions Medication interactions Hormonal or metabolic effects Unclear long-term safety Lack of monitoring Delayed treatment for an actual injury or medical condition Medical oversight is especially important for patients with autoimmune conditions, cancer history, active infections, chronic inflammatory disorders, cardiovascular concerns, hormone-sensitive conditions, or complex medication regimens

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However, it is important to realize that an important number of the patients may benefit from the medication, that hepatic, renal, cardiac or neurological deterioration and sudden unexpected death could be prevented, that the life span of erythrocytes is increased [57] and the quality of life in a variety of chronic diseases is improved (e.g