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Please remember that it may take up to eight to 12 weeks of consistently taking antidepressants as prescribed to see their full benefit and to determine whether a medication is a good fit for you or if another option may be better

Independently of the indication for depression, says Karst, I have good experience with buproprion. Other activating antidepressants that he finds helpful are duloxetine, Savella, and fluvoxamine