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Accelerated identification of cell active KRAS inhibitory macrocyclic peptides using mixture libraries and automated ligand identification system (ALIS) technology

Redox-dependent copper ion modulation of amyloid- (1-42) aggregation in vitro

Serine and glycine deprivation For all serine and glycine-deprivation experiments, cells were cultured in MEM (Gibco, 21090) supplemented with 10% dialysed FBS (Hyclone, Thermo Scientific), 1% penicillinstreptomycin, d-glucose (5 mM), sodium pyruvate (65 M), 1X MEM vitamin solution (Gibco, 11120), l-Glutamine (2 mM), l-Proline (0.15 mM), l-Alanine (0.15 mM), l-Aspartic acid (0.15 mM), l-Glutamic acid (0.15 mM) and l-Asparagine (0.34 mM) (-SG media)

It also facilitates the release of growth hormone, insulin, glucagon, and prolactin, important hormones for metabolic drive