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Ethics declarations Ethics approval and consent to participate Samples were collected in line with the Dutch Code for Proper Secondary use of Human Tissue ( and the local Medical Ethical Committee (protocol number 16-4-181)

Here we show that SCLC cells, similar to their cells of origin, pulmonary neuroendocrine cells, exhibit low activity in pathways protecting against reactive oxygen species (ROS)

These factors include age, sex, existing comorbidities, targeted symptoms, blood biomarkers, and specific treatment protocols, before fully endorsing the use of omega-3 PUFAs either as an independent treatment or in conjunction with other medications for migraine management (80)

The drugs also differ in how quickly the receptor winds down after activation (beta-arrestin recruitment)