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Current treatment options Patients with NP typically do not respond to traditional analgesics (paracetamol, NSAIDs) or weak opioids because these do not focus on treating the types of symptoms associated with NP [2]

Garvey, M

GSR variants that reduce enzyme activity or stability compromise recycling efficiency increasing the fraction of glutathione trapped as GSSG rather than available as reduced GSH for antioxidant and detoxification reactions