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doi: 10.3389/fimmu.2022.996308 142 DavisCIGuXKieferRMRalleMGadeTPBradyDC

Because of these drawbacks, the question of trace element adequacy versus toxicity is most likely to be resolved in a research setting, rather than through routine clinical monitoring

Analysis of the individual stages in the autophagy pathway revealed that the factors involved in the initiation (DEPTOR and TBK1), phagophore formation (VSP34, ATG14, and BIF1), elongation (ATG14), and completion (ATP6V1D and ATP6V1H) of autophagy were elevated in Kupffer cells, stellate cells, and sinusoidal endothelial cells of severely steatotic livers