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doi:10.1016/S1369-5266(03)00039-6

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The effects of the GM on the OVX mices bone metabolism were evaluated on antibiotic-loading gut flora models

Abbreviations EPS: Extracellular polymeric substances MDSCs: Myeloid-derived suppressor cells LPS: Lipopolysaccharides OxPhos: Oxidative phosphorylation IL-17: Interleukin-17 ETBF: Enterotoxigenic Bacteroides fragilis IBD: Inflammatory bowel diseases IL-6: Interleukin 6 STAT3: Signal transducer and activator of transcription 3 OMV: Outer membrane vesicles PCR: polymerase chain reaction IgG: Immunoglobulin G OMP: Outer membrane protein Cag: Cytotoxin-associated gene PAI: Pathogenicity island TCA: Ricarboxylic acid NADPH: Nicotinamide adenine dinucleotide phosphate ATP: Adenosine Triphosphate FAD: Flavin adenine dinucleotide LAT1: L-Type Amino Acid Transporter APCs: Antigen-presenting cells CTL: Cytotoxic T lymphocytes IL-2: Interleukin-2 IFN-: Interferon- IL-4: Interleukin-4 IL-13: Interleukin-13 IL-10: Interleukin-10 IL-23: Interleukin-23 TNF-: Tumor necrosis factor- IgG2a: Immunoglobulin G2a TCR: T-cell receptor IL-12: Interleukin 12 IL-18: Interleukin-18 IL-5: Interleukin-5 IgE: Immunoglobulin E TGF-: Transformation of the growth factor- IgM: Immunoglobulin M IgA: Immunoglobulin A Tregs: Regulatory T cells FOXP3: Forkhead box protein P3 CTLA4: Cytotoxic T-lymphocyte antigen 4 M1: Pro-inflammatory macrophages M2: Anti-inflammatory macrophages RBPJ: Recombination signal binding protein for the immunoglobulin kappa J region ARG1: Arginase 1 IRF4: Interferon regulatory factor 4 SOCS3: Cytokine signaling suppressor 3 CCL1: Chemokine ligand 1 IL-1: Interleukin-1 PMNs: Polymorphonuclear leukocytes ROS: Reactive oxygen species NET: Neutrophil extracellular trap QS: Quorum sensing AHL: N-acyl homoserine lactone CXCL2: CXC Motif Chemokine Ligand 2 INOS: Inducible nitric oxide synthase TLRs: Toll-like receptors GM-CSF: Granulocytemacrophage colony-stimulating factor VEGF: Vascular endothelial growth factor G-CSF: Granulocyte-colony stimulating factor FnBP: Fibronectin-binding protein Cas8: Caspase 8 SCV: Small colony variant IL-1R: IL-1 receptors MyD88: Myeloid differentiation primary response 88 CXCL1: Chemokine (CXC motif) ligand 1 GAPDH: Glyceraldehyde-3-phosphate dehydrogenase NFAT: Nuclear factor of activated T cells PI3K: Phosphatidylinositol 3-kinase AKT: Protein kinase B MTORC1: Mammalian target of rapamycin complex 1 CNS2: Conserved non-coding sequence 2 PPP: Pentose phosphate pathway TAMs: Tumor-associated macrophages HIF1: Hypoxia-inducible factor 1 alpha CF: Cystic fibrosis IL-8: Interleukin 8 CXCR1: CXC motif chemokine receptor 1 CXCR2: CXC motif chemokine receptor 2 LTB4: Lipid leukotriene B4 CXCR4: CXC motif chemokine receptor 4 RAGE: Receptor for Advanced Glycation Endproducts HIV: Human Immunodeficiency Virus NMR: Nuclear Magnetic Resonance M-CSF: Macrophage colony-stimulating factor References Abadi ATB