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Senescent cells secrete a toxic mix of inflammatory cytokines, proteases, and growth factors called the Senescence-Associated Secretory Phenotype (SASP)

At the University of California, Santa Barbara, says 22-year-old student Ryan Roberts, "everybody does them." The long-term health risks of this experimentation are not yet known, but doctors are worried about higher cancer risk

By degrading damaged organelles and clearing intracellular harmful substances, autophagy helps maintain cellular homeostasis and can influence the apoptotic process to some extent

For example, platinum (IV) prodrugs activated by intracellular GSH have demonstrated enhanced tumor selectivity and reduced systemic toxicity in clinical trials