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All experiments were conducted in accordance with the Guidelines for the Management and Use of Laboratory Animals and were approved by the Animal Research Committee of the National Center for Nanoscience and Technology (NCNST 21-202503-0020)

Nuclear PKM2 contributes to gefitinib resistance via upregulation of STAT3 activation in colorectal cancer

This is accompanied by podocyte injury, characterized by podocyte hypertrophy, foot process effacement and detachment of podocytes from the glomerular basement membrane

In addition, iFSP1 was shown to inhibit FSP1 in a species-dependent manner, revealing structural features that confer selectivity for the human enzyme 120