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When the oxygen supply is insufficient, a large amount of pyruvate is produced by anaerobic glycolysis and converted to lactic acid to maintain the energy supply

Compared to C group, supplementation of PJ, CM, CM and SM slightly alleviated the increased weight ratio of liver and kidney in the alcohol-treated rats

Moreover, pharmacological doses of ZnO may interact negatively with other nutrients (38), promote the acquisition of antibiotic multi-resistant genes in zoonotic pathogens such as enterotoxigenic Escherichia coli (ETEC) (39), contributing to the emergence of antimicrobial resistances (AMR) and, finally, exacerbating public health concerns (33, 40, 41)