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Once validated, they could allow ophthalmologists to identify high-risk patients, enabling them to administer more aggressive treatments when necessary while avoiding unnecessary interventions for others ( Quantdicators like IOP and OCT measurements of retinal nerve fiber layer thickness are examples of biomarkers that are already being explored for their potential to track glaucoma progression

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Since the number of sites is limited, as more sites are occupied by Hp IgG from the sample, fewer sites are left to bind Hp IgG-HRP conjugate