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It shows high potential for treating hypertension-induced cerebral small vessel disease (Xia et al., 2022) by reversing neuroinflammation through blockade of the NF-B pathway, upregulating neurotrophic factors via activation of the Tropomyosin Receptor Kinase B (TrkB) pathway, and preserving blood-brain barrier integrity

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We need to challenge current attitudes and practices to improve patient outcomes