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Front Pharmacol 15:1405423

The biologically active state responsible for antioxidant activity

More recently, tofersen (QALSODY ), an antisense oligonucleotide targeting mutant SOD1 , has shown potential in reducing NfL levels and slowing functional decline, though concerns remain regarding inflammatory side effects and the failure of initial phase III trials [7678]

J., Zhang, P., McIlhenny, S., Tulenko, T., & DiMuzio, P

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