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Thalassemias Thalassemias are disorders that are caused by the combination of over 300 known mutations in the hemoglobin chains (alpha or beta) [61]

Since the level of glutathione in the body cannot be precisely measured, the effects in people with low glutathione levels have not been clearly demonstrated

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A marked reduction was observed in protective phyla, including Bacteroidota, which was significantly decreasedcompromising SCFA production and gut homeostasisalong with a substantial depletion of Actinomycetota, a phylum containing Bifidobacterium, indicating impaired immunomodulatory capacity