glutathione s transferase and prostate cancer Frontiers The triple role of glutathione

NAD+- dependent enzymes called sirtuins have shown to benefit brain health by acting on amyloid plaques, repairing DNA, lowering inflammation, and promoting neuronal function, which in turn can prevent or delay the onset of mild cognitive decline.

Metabolic processes trigger different types of ROS, that are able to, if present at inadequate levels, oxidize DNA and induce various damage, such as double-stranded DNA breaks and deficiencies, often found in human tumors (De Bont and van Larebeke, 2004)

Lin S.-H

Transporter-mediated approach for brain delivery of drugs Great efforts have been taken to deliver drugs into the brain, which resulted in the development of several drug delivery strategies (67,68,69,70)