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Originally, psoriasis was thought to be due to dysregulation of keratinocyte proliferation (17), increasing evidence indicates a crucial role of the immune system in the pathogenesis of psoriasis (18)

CJC-1295 and ipamorelin are commonly used together because they have complementary time-release characteristics: CJC-1295 is effectively GHRH that has been modified to have a longer half-life, so it stimulates pituitary growth hormone secretion in a sustained manner over an extended period.9 Ipamorelin acts on the pituitary gland directly, inducing a more immediate dump of growth hormone into circulation

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