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It transports fatty acids into the mitochondria (the "power plants" of every cell), so that the fatty acids are then ready to produce energy

Similar to SGLT2i, some glucagon-like peptide 1 receptor agonists (GLP1RA) have demonstrated a reduction of cardiovascular endpoints in clinical trials, including MACE or CV death alone, thus resulting in a similar guideline recommendation as described before for SGLT2i [147148]

Particularly, transgenic lines that label myelin sheaths, such as Tg(MBP:eGFP-CAAX) [15], provide a valuable tool for screening pro-myelinogenesis drugs

To further investigate the molecular mechanisms underlying this phenotype, we explored a multi-omics approach, beginning with metabolomics to examine potential disruptions in amino acid metabolism