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Phase 2: Glutathione-S-Transferase and Sulpho-transferases Following phase 1, phase 2 enzymes take over the metabolites produced and attach small chemical groups to them in order to modify the solubility of the toxins and facilitate their elimination

The efficient glycolysis of tumor cells leads to an acidic environment in the tumor microenvironment

Among the measured values, box plot analysis was used to identify outliers, but no outliers were identified (data not shown)

The effectiveness of such regimens appears restricted to a particular subset of patients where drug addiction mechanisms outweigh adaptive survival pathways