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Recent studies have demonstrated that TRIM21, TRIM59, or NEDD4L promotes ferroptosis by inducing K48-linked ubiquitination and degradation of GPX4 (Sun et al

MPP + enters dopaminergic neurons via the DA transporter and inhibits mitochondrial complex I, resulting in decreased ATP levels, the subsequent apoptosis, and necrosis of dopaminergic neurons (Speciale 2002)

doi: 10.1016/j.neuron.2023.05.009 253 HuPLuYPanB-XZhangW-H

The MycoTOX Profile utilizes state-of-the-art liquid chromatography tandem mass spectrometry (LC-MS/MS) technology to ensure high specificity (or fewer false positive results) and capture free (unconjugated) mycotoxin presence even at low levels