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The inhibition of ATG5, a mediator of autophagy in hypoxic cancer, can induce cisplatin sensitivity in previously resistant cells (188), supporting the contribution of hypoxia-induced autophagy to the development of anticancer drug resistance

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If you have ever had an allergic reaction to abiraterone acetate or any other ingredients in this medicine, inform your doctor immediately before starting treatment

143,144,145 Physical barriers, such as dense stromal matrix and aberrant vasculature, further impede immune cell infiltration and intratumoral drug distribution