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However, since this reaction occurs primarily in the liver, glycine deficiency could impede the elimination of excess acylCoAs from the liver of individuals with obesity and contribute to MASLD pathogenesis

With the current consensus that cellular ROS could drive important biological signaling pathways through redox signaling, researchers have started to investigate the role of cellular ROS in the pathogenesis of neurodegenerative diseases

Zhu Z., Chen G., Yu S., et al., Circadian Clock Disruption Stimulates Bone Loss via Regulatory T CellMediated Regulation of IL10 Expression, International Immunopharmacology 139 (2024): 112589