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The small number of patients who received a CTLA-4 inhibitor, a PD-1/PD-L1 inhibitor, or a combination of immune checkpoint inhibitors limits the comparison between our findings and the findings in other studies related to these checkpoint inhibitor classes

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Because patients with COVID-19 have evidence of systemic inflammation, often have their course complicated by acute respiratory distress syndrome, and may have respiratory mucus buildup limiting adequate airflow, systemic or aerosolized N -acetylcysteine (or both) may be beneficial in this specific patient population