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Manganese-containing SOD mimics, in particular Mn-based porphyrins, are particularly effective

22 , 1827 (2020 Rajer, F., Allander, L., Karlsson, P

Disclosure of interest: Nothing to disclosure E-Posters - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION 06.00 - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION - 06.01 - PATHOPHYSIOLOGY OF STROKE / TRANSLATIONAL MEDICINE P2594 - ESOC25-2450 CONSEQUENCE OF EARLY AND LATE THROMBOLYSIS FOLLOWING ISCHEMIC STROKE ON BRAIN METABOLIC PROFILES EVALUATED BY 9.4 T MR SPECTROSCOPY Henrik Andersson 1 , Kajsa Arkelius 1 , Michael Gottschalk 1 , Saema Ansar 1 1 Lund University, Lund, Sweden Background and Aims: Ischemic stroke is a significant contributor to mortality and disability worldwide

Table 1 Effects of Yang- and Qi-invigorating Chinese tonifying herbs on ATP-GC and reduced glutathione (GSH) levels in cultured H9c2 cardiomyocytes [modified from (9)] Full table On the other hand, Qi-invigorating herbal extracts were found not able to stimulate mitochondrial ATP-GC following a 4 h incubation, whereas all of them stimulated ATP-GC in H9c2 cells following incubation for 24 h ( Table 1 )