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There are three types of autophagy, each differing in morphology and mechanism, but leading to the degradation of cellular components within lysosome (Parzych and Klionsky, 2014)

It is derived from several observations, including the inability of antibodies to minor populations of surface proteins for example, antibodies to NA on influenza viruses or to an altered conformation of the rabies G protein to neutralize the corresponding viruses owing to insufficient coating of virions