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Deep breathing exercises or listening to calming music can help reduce anxiety and create a more comfortable environment

Long-term metformin use is associated with B12 deficiency in approximately 10-30% of patients, with risk increasing with duration of therapy and higher doses

Acknowledgements We would like to additionally thank Nicole Coursen for helping with animal and sample collection, as well as Kuni Suzuki and the Macauley Lab at the University of Alberta for their expertise and help with the Meso Scale Discovery technology

Banitalebi Dehkordi M, Madjd Z, Chaleshtori MH, Meshkani R, Nikfarjam L, Kajbafzadeh AM