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2c,d and 3a)

Interestingly, TSP-1 is also a well-documented regulator of the TGF superfamily in fibrotic diseases (Murphy-Ullrich and Suto, 2018)

While glia-derived glutamine provides 50-60% of glutamate neurotransmitter, when the pathway is blocked with MeAIB excitatory transmission abruptly decreases but rapidly recovers, consistent with endogenous neuronal sources of glutamate neurotransmitter (15)