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egl-9 hif-1 double mutants rescued by the odIs131 transgene)

Middle East Fertil Soc J

In addition to thiosemicarbazone derivatives, thiosemicarbazide and its derivatives 378381 , 5-benzylidene(thio)barbiturate-beta-d-glycosides 382 , n -alkyl 383 , p -phenylene-bis, phenyl 384 , benzyl, p -xylidine-bis and p -pyridine dithiocarbamate sodium salts 385 , diethyldithiocarbamate, phenylthiourea 3 86 and other thiourea derivatives (Figure 12) such as methimazole, thiouracil, methylthiouracil, propylthiouracil, ambazone, and thioacetazone 387 have been identified as tyrosinase inhibitors

These insulin-sensitizing effects of LXR repression may offer additional cardioprotective benefit to that attributable to improvements in circulating lipids 56