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evaluated the pharmacodynamics, pharmacokinetics, safety, and tolerability of the single and multiple up-dose oral FPN inhibitor VIT-2763 in healthy volunteers and found that VIT-2763 has a safety profile similar to placebo and is well tolerated, with no serious adverse events and discontinuations due to adverse events

During the reevaluation process, the measure developer and Clinician Expert Workgroup reviewed testing results that showed risk adjustment effectively mitigated cost differences between the three subgroup populations, which is expected based on the design of the risk adjustment model

Characterization and quantitation of busulfan DNA adducts in the blood of patients receiving busulfan therapy

3 With elucidation of its mechanism, incidence, and impact on resistance to chemotherapy, interventions to decrease target concentrations of GSH may become part of future oncologic therapeutic regimens