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If your urine is very dark or orange, consider making an appointment sooner than later, as liver dysfunction can make this happen

Common signs are: Fatigue and weakness Neurological changes, such as numbness or tingling in extremities Megaloblastic anemia, characterized by large, abnormal red blood cells We urge quick medical help if these signs dont go away

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However, its high sensitivity in detecting minimal residual disease (MRD) may lead to lower CR response rates, thus hindering comparisons with results obtained by immunofixation at different time points or in other studies [56]