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Such studies have shown BBB dysfunction in patients with AD and other neurodegenerative disorders such as PD, ALS, and MS, which is also supported by biofluid biomarker data and postmortem studies [190]

Our results support the theory that cancer patients are deficient in vitamin C, and that tumors and other tissues act as vitamin C sinks, so that extra IVC treatments are needed in order to replenish depleted stores: For a given dose of IVC, cancer patients, on average, achieved lower plasma ascorbate increases compared to healthy adults

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Compared to CDK 4/6 inhibition alone, preclinical research showed that CDK 4/6 inhibition during or after RT induced DNA double-strand break repair and enhanced tumor cell death (O'Brien et al