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doi: 10.1016/j.nantod.2016.04.008 97 Van NielGDAngeloGRaposoG

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Symptoms include vomiting, diarrhea, jaundice (yellowing of the skin and eyes), and, in severe cases, neurological issues like seizures

For example, P301S mice have been observed to spend relatively more time in open arms of EPM or in the center area of OFT compared to wildtype control, while they may exhibit sexual dimorphism (Dumont et al., 2011