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The reaction is catalyzed by glutathione S-transferase and the level of total glutathione can be detected by fluorometer or fluorometric plate reader

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Glutathione S-transferase variants increase susceptibility for late-onset Alzheimer's disease: association study and relationship with apolipoprotein E epsilon4 allele

Additionally, studies have examined how a lack of melatonin affects specific brain functions, such as the regulation of sphingolipid turnover in the hippocampus, which suggests that melatonin is involved in maintaining a balance of lipids, and that this equilibrium may be compromised in aging organisms (Tchekalarova et al