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However, studies showing that SnPP is a photosensitizer of bilirubin destruction in vitro (McDonagh and Palma, 1985), and phototoxic in vivo (Hintz et al., 1990) led to its abandonment for use in human infants

Pro-inflammatory cytokines play a central role in the pathophysiology of endometriosis, with elevated levels observed in both local (peritoneal fluid, ectopic lesions) and systemic (serum) compartments

The effective blood-brain barrier mechanism impeding the transport of monoamines has been attributed to both the presence of tight junctions cementing adjacent endothelial cells of the cerebral capillary walls, along with high concentrations of dopa decarboxylase and monoamine oxidase (MAO) in the cerebral capillary endothelium (Bertler et al, 1966