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Conclusion: While A1AT PI*MZ variant significantly increases the risk of liver related events in patients with non-lean NAFLD, it interestingly, did not seem to significantly increase the risk of developing hepatic events in patients with lean-NAFLD

Serum lipid peroxidation and antioxidant enzyme levels in male and female diabetic patients

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Relative level of ROS was detected centrifuging liver tissue in the appropriate buffer (20 mmol/L Tir-HCl (pH 7.4), 20 mmol/L NaH 2 PO 4 , 5 mmol/L MgCl 2 , 130 mmol/L KCl and 30 mmol/L glucose) and incubating the supernatant with DCFH-DA (2, 7-dichlorodihydrofluorescein diacetate) for 15 min at 37 C