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Description

Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles

Treatment duration varied from 1 week to 7 weeks

These findings suggest that catalpol has significant beneficial effects on atherosclerosis and other vascular-related diseases

The crystal structures, along with the activity assays of UGT74F2 and UGT74F1 mutants, suggest that SA can bind in two different conformations, with each enzyme preferring a particular SA binding mode