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Data on new targeted therapies are even more promising: vedolizumab, as a gut-specific anti-integrin, has demonstrated a rare incidence of severe adverse events in registered trials, open extensions, and real-world data, while remaining safe in pregnant patients, children, the elderly, and those with a history of cancer [334]

In vitro studies using ovarian cancer cell lines A2780 and SKOV3 reveal that SLT reduces cell viability by activating a ROS-mediated p53 pathway, resulting in G1 cell cycle arrest, enhanced apoptosis, and inhibition of cell migration and invasion

cerevisiae strain was maintained on Y east E xtract P eptone D extrose (YEPD) agar medium and grown in liquid YEPD medium at 30 C with aeration on a shaker

Scand J Work Environ Health