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The advantage of using ageing protocols is to fasten the appearance of metabolic alterations resulting in the accumulation of toxic compounds

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Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3)

Furthermore, increased number of hypodense eosinophils was observed in bronchoalveolar lavage eosinophils following an antigen-challenge (Kroegel et al., 1994)