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Autophagy, i.e., the internal mechanism for recycling, biosynthesis and degradation of constituents and organelles via lysosomes, is probably the most essential universal process for the survival of all kinds of cells (He and Klionsky, 2009)

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As an alternative tracer technology, fluorescence imaging poses significant superiority over the above medical imaging approaches in tumor interventions, benefiting from its high sensitivity, non-invasive, and fast feedback, thus, having attracted widely interesting [9], [10], [11], [12]

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