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A recent stereopathological study on the uterus and ovaries of LE-induced PCOS mice also demonstrated that NAC, similar to metformin, could significantly reverse the pathological phenotypes to those of normal mice [42]

In the United States alone, APAP misuse accounts for approximately 500 deaths annually, in addition to nearly 100,000 poisoning-related emergency calls, 50,000 emergency department visits, and 10,000 hospitalizations (67)