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As a result, using antioxidants (e.g., quercetin and vitamin E) was considered as a clinical therapy for DKD patients, but the trials are still at the stage of animal studies[95, 96]

doi: 10.1159/000228994 7 LibertiMVLocasaleJW

The genome editing methods are based on the manipulations of the nucleotide sequences in a strictly specified location and with a minimum number of off-target changes in the genome, and are supposed to be environmentally friendly