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Signaling network analysis on healthy human IVD cells also found that platelet-derived growth factor (PDGF) and TGF- cascades are necessary cues in the formation and maintenance of the NP microenvironment (Gan et al., 2021)

First isolated from the cerebral venous blood of rabbits in 1977, this nine-amino-acid peptide has captured the attention of researchers worldwide for its remarkable effects on sleep regulation, stress response, and neuroendocrine function

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