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The compounds ability to activate the Nrf2-mediated antioxidant response helps mitigate the collateral damage caused by radiation and chemotherapy, particularly in highly vulnerable tissues such as hematopoietic systems and mucosal barriers ( 5.2 Clinical evidence and trial outcomes The translation of SFN from preclinical models to human clinical applications has generated substantial evidence supporting its potential in cancer prevention and management

Without adequate copper availability through GHK-Cu, newly formed collagen fibers cannot achieve proper structural cross-linking, making them vulnerable to rapid degradation by metalloproteinases

Continuous variables were expressed as mean standard deviation (SD)