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Furthermore, while 4-HNE promotes cyst growth via multiple kinase pathways (270), the hierarchical integration of these pathways (e.g., which is the rate-limiting step) and their crosstalk with ferroptosis core networks (e.g., lipid peroxidation amplification) are poorly defined

Flippases, namely P4-ATPases like ATP11A and ATP11C, actively translocate aminophospholipids (PS and PE) from the outer to the inner leaflet by an ATP-dependent mechanism (42, 45)

Synergism of non-thermal plasma and low concentration RSL3 triggers ferroptosis via promoting xCT lysosomal degradation through ROS/AMPK/mTOR axis in lung cancer cells

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