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Due to its lipophilic nature, NFPS tends to accumulate within the plasma membrane, diffusing through the lipid bilayer until it reaches GlyT1

Upon activation, Nrf2 translocates to the nucleus, binds specifically to the Antioxidant Response Element (ARE) and induces transcription of downstream genes (Baird and Dinkova-Kostova, 2011) (Figure 2B)

Introduction The functional role of Red Blood Cells (RBCs) is the transport of oxygen from the lungs to the tissues providing the oxygen required by all cells and tissues

Although many clinical trials suggested that patients with MetS have more propensity for ED, it is difficult for these cross-sectional studies or meta-analysis to elucidate how MetS induce ED