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These strains are classified as variants of concern (VOCs) [17], as the N501Y mutation present in variants from the UK (Alfa), South Africa (Beta), and Brazil (Gamma) that has shown an increase in ACE2 affinity causing enhanced infectivity and more severe COVID-19 [8, 18]

Results: Treatment with NTZ lessened the serum liver enzymes, reduced malondialdehyde (lipid peroxidation product), enhanced antioxidant capacity, attenuated proinflammatory cytokines, and suppressed apoptosis

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The pentose phosphate pathway also produces pentose, another important part of NAD(P)H, from glucose