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Unfortunately, the widely held belief that it is safe for pediatric use is based on numerous clinical studies that assume that the liver is the target of drug toxicity [5]

PMCID: PMC6140912

doi: 10.7759/cureus.86188

Another therapeutic approach with promising potential has been recently proposed by Wang and colleagues, who reported that significant elevation of IGF-1 levels could be achieved by combination treatment with tadalafil (TAD) and hydroxychloroquine HCQ