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Orally delivered NAC undergoes extensive first-pass metabolism resulting in about 90% loss by enzymic deacylation to form cysteine in the small intestine [9]

Additionally, rats given TNBS experienced severe bloody diarrhea, an increased colon weight-to-length ratio, a macroscopic damage score, goblet cell loss, submucosal edema, increased inflammatory cell infiltration, and a marked weight loss (259)

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The most sought-after traits by blueberry breeders are larger size, better flavour, increased bloom (coating of wax), easy detachment of fruit for harvesting by hand or machine, minimum scarring where fruit detaches from the pedicel, firmness, and long shelf life [14,19]