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Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. New England Journal of Medicine , 2021

For MS analysis, a positive ion mode (SIM) was used to monitor the m/z of dihexa at 527nm (dihexa with the addition of a sodium adduct) and the m/z of Nle-YI-(6) aminohexanoic amide and Nle 1 - AnglV (internal standards) at 513 and 541 , respectively (both with sodium adducts)