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[67] demonstrated that sevoflurane can reduce neuronal apoptosis by mediating the E2F transcription factor 1/enhancer of zeste homolog 2/tissue inhibitor of metalloproteinases 2 (E2F1/EZH2/TIMP2) regulation axis, thereby protecting rats from brain I/R injury

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Fertil Steril (2011) 96(2):3605

Psoriatic skin lesions contain high numbers of CD4 + T cells that produce IL-17, indicating that Th17 cells play a crucial role in the immunopathogenesis of psoriasis (Fujishima et al