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Among the most promising targets for such strategies are certain types of cancer, neurodegenerative diseases (e.g., Alzheimers disease and Parkinsons disease), and chronic inflammatory disorders ( Additionally, studies evaluating the role of ATs in human diseases rarely define which specific ROS are involved, their sources, how they reach their molecular targets, and which targets are affected, and why

As indoleamine 2,3-dioxygenase (IDO) is a key enzyme for the degradation of trp in kyn, IDO activity is reflected in the trp/kyn (TKR) ratio

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Y-YY contributions to design of the work and revised the work